14 Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

13 Van Andel Research Institute, Grand Rapids, MI 49503, USA.

12 Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, USA.

11 Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada.

10 Institute for Systems Genetics, NYU Grossman School of Medicine, New York, NY 10016, USA Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY 10016, USA.

9 Sema4, a Mount Sinai venture, Stamford, CT 06902, USA.

8 Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.

7 Department of Oncology, Johns Hopkins University, Baltimore, MD 21205, USA.6 The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD 21287, USA.5 Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.4 Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA 02142, USA.Louis, MO 631110, USA McDonnell Genome Institute, Washington University in St. 3 Department of Medicine, Washington University in St.2 Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA.1 Department of Pathology, Johns Hopkins University, Baltimore, MD 21231, USA.Mitual Amin, Eunkyung An, Christina Ayad, Thomas Bauer, Chet Birger, Michael J Birrer, Simina M Boca, William Bocik, Melissa Borucki, Shuang Cai, Steven A Carr, Sandra Cerda, Huan Chen, Steven Chen, David Chesla, Arul M Chinnaiyan, Antonio Colaprico, Sandra Cottingham, Magdalena Derejska, Saravana M Dhanasekaran, Marcin J Domagalski, Brian J Druker, Elizabeth Duffy, Maureen A Dyer, Nathan J Edwards, Matthew J Ellis, Jennifer Eschbacher, Alicia Francis, Jesse Francis, Stacey Gabriel, Nikolay Gabrovski, Johanna Gardner, Gad Getz, Michael A Gillette, Charles A Goldthwaite Jr, Pamela Grady, Shuai Guo, Pushpa Hariharan, Tara Hiltke, Barbara Hindenach, Katherine A Hoadley, Jasmine Huang, Corbin D Jones, Karen A Ketchum, Christopher R Kinsinger, Jennifer M Koziak, Katarzyna Kusnierz, Tao Liu, Jiang Long, David Mallery, Sailaja Mareedu, Ronald Matteotti, Nicollette Maunganidze, Peter B McGarvey, Parham Minoo, Oxana V Paklina, Amanda G Paulovich, Samuel H Payne, Olga Potapova, Barbara Pruetz, Liqun Qi, Nancy Roche, Karin D Rodland, Daniel C Rohrer, Eric E Schadt, Alexey V Shabunin, Troy Shelton, Yvonne Shutack, Shilpi Singh, Michael Smith, Richard D Smith, Lori J Sokoll, James Suh, Ratna R Thangudu, Shirley X Tsang, Ki Sung Um, Dana R Valley, Negin Vatanian, Wenyi Wang, George D Wilson, Maciej Wiznerowicz, Zhen Zhang, Grace Zhao Clinical Proteomic Tumor Analysis Consortium

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